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Primary Antibodies
Bestrophin-1 Antibody
Bestrophin-1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C47488
Reactivity:Human,Rat,Mouse
Applications:WB,IHC,IF
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Bestrophin-1 Antibody

Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using Bestrophin-1 Rabbit pAb diluted at 1:200.

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Product Details
Product Name
Bestrophin-1 Antibody
Description
This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008],
Catalog No
C47488
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Bestrophin-1 (TU15B; Vitelliform macular dystrophy protein 2)
Molecular Weight (Da or kDa)
Gene Name
BEST1
Protein Name
Bestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)
Human Gene ID
7439
Human Swiss Prot No.
O76090
Immunogen
Synthetic Peptide of Bestrophin-1 AA range: 161-211
Specificity
The antibody detects endogenous Bestrophin-1 protein
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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