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TLR2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C47553
Reactivity:Human,Mouse,Rat
Applications:IHC,IF
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
Product Details
Product Name
TLR2 Antibody
Description
The protein encoded byThis gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Catalog No
C47553
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
IHC, IF
Dilution
IHC 1:200-500. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
Storage and Stability
Store at -20°C/1 year
Other Name
TLR2; TIL4; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; CD282
Molecular Weight (Da or kDa)
Gene Name
TLR2
Protein Name
Toll-like receptor 2
Human Gene ID
7097
Human Swiss Prot No.
O60603
Immunogen
Recombinant Protein of TLR2
Specificity
The antibody detects endogenous TLR2 protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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