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Primary Antibodies
tPA/PLAT (AX2828) Rabbit mAb
tPA/PLAT (AX2828) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M0828
Reactivity:Human,Mouse,Rat
Applications:WB,IF/ICC,ELISA
Modifcation:Unmodified
Source:Rabbit
Storage and Stability:Store at -20℃/ 1 year. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20ul Size Available
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tPA/PLAT (AX2828) Rabbit mAb

Confocal imaging of human placenta using tPA/PLAT Rabbit mAb (M0828,at dilution of 1:100) (Red). DAPI was used for nuclear staining (blue). Objective: 40x. Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IF staining protocol.

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Product Details
Product Name
tPA/PLAT (AX2828) Rabbit mAb
Description
This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Catalog No
M0828
Reactivity
Human, Mouse, Rat
Applications
WB, IF/ICC, ELISA
Application Dilutions
WB,1:1000 - 1:6000 | IF/ICC,1:100 - 1:400 | ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modifcation
Unmodified
Source
Rabbit
Isotype
IgG
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 463-562 of human tPA/tPA/PLAT (P00750).
Calculated MW (kDa)
63kDa
Observed MW (kDa)Gene Name
70kDaPLAT
Other Name
TPA; T-PA; tPA/PLAT
Gene ID
5327
Human Swiss Prot
P00750
Formulation
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃/ 1 year. Avoid freeze / thaw cycles.
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Primary Antibodies

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