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E-Cadherin (AB1402) mouse mAb
E-Cadherin (AB1402) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0339
Species Reactivity:Human;
Application:IHC; WB; IF; ELISA
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
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E-Cadherin (AB1402) mouse mAb

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Product Details
Product Name
E-Cadherin (AB1402) mouse mAb
Description
E-Cadherein, 120kDa, is a critical regulator of epithelial junction formation. The E-cadherin internal domain binds with alpha, beta, gamma, and p120 catenins to anchor the ECAD complex to the actin cytoskeleton of the cell. E-cadherin is expressed in virtually all epithelial cells with the exception of adrenocortical cells. The expression in liver cells is weaker than in most other epithelia. ECAD is also expressed in melanocytes (adhering to squamous epithelial cells) . Mesothelial cells and granulosa cells are ECAD negative. Mesenchymal cells and neural crest cells are mostly negative but some types may show a weak reaction. Testicular germinative cells are weakly positive. At present, it is commonly used to differentiate breast lobular cancer from ductal cancer (the former is often negative, the latter is often positive) .
Catalog No
W0339
Species Reactivity
Human;
Clonality
Monoclonal
Host
Mouse
Modifcation
Unmodified
Clone
AB1402
Isotype
IgG2b, kappa
Application
IHC; WB; IF; ELISA
Application Dilutions
IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to the amino acid region 700 - 800 of the human E - Cadherin protein.
Specificity
The antibody can specifically recognize E-cadherin protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein G affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
CDH1
Gene ID
999
Human swiss
P12830
Protein Name
E-Cadherin
Synonyms
Cadherin-1, CAM 120/80, Epithelial cadherin (E-cadherin) , Uvomorulin, CD324, CDH1, CDHE
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