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MGMT (AB2445) mouse mAb
MGMT (AB2445) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0164
Species Reactivity:Human;
Application:WB; IF; ELISA
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
Product Details
Product Name
MGMT (AB2445) mouse mAb
Description
O-6-methylguanine-DNA methyltransferase (MGMT) Homo sapiens Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O (6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015],
Catalog No
W0164
Species Reactivity
Human;
Clonality
Monoclonal
Host
Mouse
Modifcation
Unmodified
Clone
AB2445
Isotype
IgG2b, kappa
Application
WB; IF; ELISA
Application Dilutions
WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to the amino acid region 1 - 100 of the human MGMT protein.
Specificity
This antibody detects endogenous levels of MGMT protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein G affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
MGMT
Gene ID
4255
Human swiss
P16455
Protein Name
MGMT
Synonyms
Methylated-DNA-- protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase (MGMT) , O-6-methylguanine-DNA-alkyltransferase, MGMT
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