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Primary Antibodies
Cleaved-PARP-1 (G215) Antibody
Cleaved-PARP-1 (G215) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: L0366
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Modification:Cleaved Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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Cleaved-PARP-1 (G215) Antibody

Western blot analysis of lysates from NIH/3T3 cells, treated with etoposide 25uM 1h, using PARP (Cleaved-Gly215) Antibody. The lane on the right is blocked with the synthesized peptide.

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Product Details
Product Name
Cleaved-PARP-1 (G215) Antibody
Description
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Catalog No
L0366
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
Modification
Cleaved Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Molecular Weight (Da)
113084
Gene Name
PARP1
Protein Name
Poly [ADP-ribose] polymerase 1
Human Gene ID
142
Human Swiss Prot No.
P09874
Immunogen
The antiserum was produced against synthesized peptide derived from human PARP. AA range:196-245
Specificity
Cleaved-PARP-1 (G215) Polyclonal Antibody detects endogenous levels of fragment of activated PARP-1 protein resulting from cleavage adjacent to G215.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (5)
The role of SIRT1 in BMP2-induced chondrogenic differentiation and cartilage maintenance under oxidative stress.

Author: Yang Lu, Li Zhou, Lijun Wang, Shan He, Honglei Ren, Nian Zhou, Zhenming Hu

Date of Publication : 2020-05-01

Mangiferin improves hepatic damage-associated molecular patterns, lipid metabolic disorder and mitochondrial dysfunction in alcohol hepatitis rats

Author: Mengran Li, Chunxiao Wu, Hongbin Guo, Ce Chu, Mingye Hu, Chengyan Zhou

Date of Publication : 2019-05-10

Sodium butyrate induces autophagic apoptosis of nasopharyngeal carcinoma cells by inhibiting AKT/mTOR signaling

Author: Wei Huang, Chong Zeng, Jie Liu, Li Yuan, Weidong Liu, Lei Wang, Hecheng Zhu, Yang Xu, Yi Luo, Dan Xie, Xingjun Jiang, Caiping Ren

Date of Publication : 2019-04-22

Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice

Author: Wang, Bin, Zhang, Yingying, Dong, Hongli, Gong, Siyi, Wei, Bin, Luo, Man, Wang, Hongyan, Wu, Xiaohui, Liu, Wei, Xu, Xingshun, Zheng, Yufang, Sun, Miao

Date of Publication : 2018-05-03

Exogenous Adipokine Peptide Resistin Protects Against Focal Cerebral Ischemia/Reperfusion Injury in Mice

Author: Zhu, Jiangtao, Wu, Di, Zhao, Chenyu, Luo, Man, Hamdy, Ronald C., Chua, Balvin H. L., Xu, Xingshun, Miao, Zhigang

Date of Publication : 2017-06-12

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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