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Primary Antibodies
Bax Antibody
Bax Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C0132
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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Bax Antibody

Western Blot analysis of 293T using Bax Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalogNo.:SA0002) was diluted at 1:20000

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Product Details
Product Name
Bax Antibody
Description
The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.
Catalog No
C0132
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
BAX; BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4
Molecular Weight (Da)
21184
Gene Name
BAX
Protein Name
Apoptosis regulator BAX
Human Gene ID
581
Human Swiss Prot No.
Q07812
Immunogen
The antiserum was produced against synthesized peptide derived from human Bax. AA range:1-50
Specificity
Bax Polyclonal Antibody detects endogenous levels of Bax protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (8)
Hydroxysafflor Yellow A Attenuates Hydrogen Peroxide-Induced Oxidative Damage on Human Umbilical Vein Endothelial Cells

Author: Xie Yuefeng, Guo Yan, Cao ShiDong, Xue Miaomiao, Fan ZhaoYue, Gao ChengXian, Jin Bo

Date of Publication : 2020-11-04

The Protective Effect of Aromatase on NSC-34 Cells with Stably Expressed hSOD1-G93A

Author: Lina Yan, Weijing Qi, Yaling Liu, Fuling Zhou, Yafei Wang, Lin Bai, Xiaomeng Zhou, Can Sun, Xiangyu Nie, Shiru Duan, Jina Ran, Juan Chen, Yingxiao Ji, Yakun Liu, Zhongyao Li, Yuanyuan Li, Qingxin Wang

Date of Publication : 2019-05-23

Specific inhibitor of Notch‑3 enhances the sensitivity of NSCLC cells to gemcitabine

Author: Bi‑Dan Hu, Jia Guo, Yuan‑Zi Ye, Ting Du, Chun‑Song Cheng, Qian Jiang, Ruo‑Nan Liu, Yan‑Bei Zhang

Date of Publication : 2018-07-01

Effects of Ovariectomy in an hSOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

Author: Lina Yan, Yaling Liu, Can Sun, Qian Zheng, Pengli Hao, Jingxu Zhai, Yuanyuan Liu

Date of Publication : 2018-02-02

Synergistic Effect of Notch-3-Specific Inhibition and Paclitaxel in Non-Small Cell Lung Cancer (NSCLC) Cells Via Activation of The Intrinsic Apoptosis Pathway

Author: Fenglian He, Ting Du, Qian Jiang, Yanbei Zhang

Date of Publication : 2017-08-03

Effect of annexin A7 suppression on the apoptosis of gastric cancer cells

Author: Ye, Weihua, Li, Yong, Fan, Liqiao, Zhao, Qun, Yuan, Hufang, Tan, Bibo, Zhang, Zhidong

Date of Publication : 2017-02-07

N′-[(3-[benzyloxy]benzylidene]-3,4,5-trihydroxybenzohydrazide (1) protects mice against colitis induced by dextran sulfate sodium through inhibiting NFκB/IL-6/STAT3 pathway

Author: Meiyang Xi, Xiaojian Wang, Jun Ge, Dali Yin

Date of Publication : 2016-06-13

Enhanced autophagy reveals vulnerability of P-gp mediated epirubicin resistance in triple negative breast cancer cells

Author: Li-han Zhang, Ai-jun Yang, Min Wang, Wei Liu, Chen-yu Wang, Xiao-feng Xie, Xu Chen, Jing-fei Dong, Min Li

Date of Publication : 2016-01-14

Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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