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Thyroglobulin Antibody

Catalog No : C30844
  • Reactivity
    Human,Mouse,Rat
  • Applications
    IHC-p,IF(paraffin section),ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Details
  • Product Name
    Thyroglobulin Antibody
  • Description
    Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
  • Catalog No
    C30844
  • Reactivity
    Human, Mouse, Rat
  • Applications
    IHC-p, IF(paraffin section), ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    IHC-p 1:50-200, ELISA 1:10000-20000
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    Thyroglobulin (Tg)
  • Molecular Weight (Da)
  • Gene Name
    TG
  • Protein Name
    Thyroglobulin (Tg)
  • Human Gene ID
    7038
  • Human Swiss Prot No.
    P01266
  • Immunogen
    Synthetic peptide from human protein at AA range: 2511-2560
  • Specificity
    The antibody detects endogenous Thyroglobulin
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.