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MBD2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C41093
Reactivity:Human,Mouse
Applications:WB
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
Product Details
Product Name
MBD2 Antibody
Description
DNA Methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a Methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to Methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from Methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the Methylation signal. It is also reported that the this protein functions as a deMethylase to activate transcription, as DNA Methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Catalog No
C41093
Reactivity
Human, Mouse
Applications
WB
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
WB 1:500-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Molecular Weight (Da)
45210
Gene Name
MBD2
Protein Name
MBD2
Human Gene ID
8932
Human Swiss Prot No.
Q9UBB5
Immunogen
Synthesized peptide derived from human MBD2
Specificity
This antibody detects endogenous levels of MBD2 at Human/Mouse
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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