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Primary Antibodies
PEN2 Antibody
PEN2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C41286
Reactivity:Human,Mouse,Rat
Applications:IHC-p,IF(paraffin section)
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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PEN2 Antibody

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Product Details
Product Name
PEN2 Antibody
Description
Presenilins, which are components of the gamma-secretase Protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Catalog No
C41286
Reactivity
Human, Mouse, Rat
Applications
IHC-p, IF(paraffin section)
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
IHC-p 1：50-200
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Molecular Weight (Da)
11110
Gene Name
PSENEN PEN2 MDS033
Protein Name
PEN2
Human Gene ID
55851
Human Swiss Prot No.
Q9NZ42
Immunogen
Synthesized peptide derived from human PEN2
Specificity
This antibody detects endogenous levels of PEN2 at Human/Mouse/Rat
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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