Order your 5 sample sized mAbs. Code: 5477

Order your Buy 1 get 1 on select products. Code: B1G1

Sign In/Register 0

We use cookies, check our Privacy Policies.

RFX5 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C41420
Reactivity:Human,Mouse
Applications:WB
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
Product Details
Product Name
RFX5 Antibody
Description
A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear Protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq, Jul 2008]
Catalog No
C41420
Reactivity
Human, Mouse
Applications
WB
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
WB 1:500-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Molecular Weight (Da)
67760
Gene Name
RFX5
Protein Name
RFX5
Human Gene ID
5993
Human Swiss Prot No.
P48382
Immunogen
Synthesized peptide derived from human RFX5
Specificity
This antibody detects endogenous levels of RFX5 at Human/Mouse
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Related Products