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Primary Antibodies
PI 3-kinase p110α Antibody
PI 3-kinase p110α Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: R12-2305
Reactivity:Human,Mouse,Rat
Applications:IF/ICC,WB,IHC-p,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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PI 3-kinase p110α Antibody

Western Blot analysis of HELA cells using PI 3-kinase p110α Polyclonal Antibody diluted at 1:2000

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Product Details
Product Name
PI 3-kinase p110α Antibody
Description
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016]
Catalog No
R12-2305
Reactivity
Human, Mouse, Rat
Applications
IF/ICC, WB, IHC-p, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
PIK3CA; Phosphatidylinositol 4; 5-bisphosphate 3-kinase catalytic subunit alpha isoform; PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit
Molecular Weight (Da)
124284
Gene Name
PIK3CA
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Human Gene ID
5290
Human Swiss Prot No.
P42336
Immunogen
The antiserum was produced against synthesized peptide derived from human PI 3-kinase p110alpha. AA range:470-519
Specificity
PI 3-kinase p110α Polyclonal Antibody detects endogenous levels of PI 3-kinase p110α protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (5)
Over-Expression of Centromere Protein U Participates in the Malignant Neoplastic Progression of Breast Cancer

Author: Hao Xiaomeng, Qiu Yufan, Cao Lixia, Yang Xiaonan, Zhou Dongdong, Liu Jingjing, Shi Zhendong, Zhao Shaorong, Zhang Jin

Date of Publication : 2021-03-23

CD90 affects the biological behavior and energy metabolism level of gastric cancer cells by targeting the PI3K/AKT/HIF‑1α signaling pathway

Author: Lu Gao, Jun Li, Junyu He, Lin Liang, Zhengxi He, Chunxue Yue, Xi Jin, Gengqiu Luo, Yanhong Zhou

Date of Publication : 2021-01-07

CD38 is involved in cell energy metabolism via activating the PI3K/AKT/mTOR signaling pathway in cervical cancer cells

Author: Shan Liao, Lin Liang, Chunxue Yue, Junyu He, Zhengxi He, Xi Jin, Gengqiu Luo, Yanhong Zhou

Date of Publication : 2020-07-01

Deficiency in the short‐chain acyl‐CoA dehydrogenase protects mice against diet‐induced obesity and insulin resistance

Author: Yulong Chen, Jinglu Chen, Caixia Zhang, Shanshan Yang, Xueping Zhang, Yin Liu, Zhiguang Su

Date of Publication : 2019-10-04

Structural characterization of a pectic polysaccharide from Codonopsis pilosula and its immunomodulatory activities in vivo and in vitro

Author: Pei Zhang, Linhai Hu, Ruibin Bai, Xiaoping Zheng, Yuling Ma, Xia Gao, Bolu Sun, Fangdi Hu

Date of Publication : 2017-06-06

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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