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Primary Antibodies
NPHP1 Antibody
NPHP1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C42023
Reactivity:Human,Mouse
Applications:WB,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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NPHP1 Antibody

Wang, Bin, et al. "Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice." Cell death & disease 9.5 (2018): 520.

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Product Details
Product Name
NPHP1 Antibody
Description
This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding diffe
Catalog No
C42023
Reactivity
Human, Mouse
Applications
WB, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Molecular Weight (Da)
Gene Name
NPHP1 NPH1
Protein Name
Nephrocystin-1 (Juvenile nephronophthisis 1 protein)
Human Gene ID
4867
Human Swiss Prot No.
O15259
Immunogen
Synthesized peptide derived from human protein . at AA range: 510-590
Specificity
NPHP1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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Publications (1)
Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice

Author: Wang, Bin, Zhang, Yingying, Dong, Hongli, Gong, Siyi, Wei, Bin, Luo, Man, Wang, Hongyan, Wu, Xiaohui, Liu, Wei, Xu, Xingshun, Zheng, Yufang, Sun, Miao

Date of Publication : 2018-05-03

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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