Description
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Reactivity
Human, Mouse, Rat
Applications
IHC-p, IF(paraffin section)
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
IHC-p 1:50-300
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Autophagy protein 5 (APG5-like) (Apoptosis-specific protein); YM3780
Molecular Weight (Da)
Gene Name
ATG5 APG5L ASP
Protein Name
Autophagy protein 5 (APG5-like) (Apoptosis-specific protein)
Human Gene ID
9494
Human Swiss Prot No.
Q9H1Y0
Immunogen
Recombinant Protein of ATG5
Specificity
The antibody detects endogenous ATG5 protein
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
