CP27B Antibody (C43240) | Assay Biotech Inc.

CP27B Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C43240

Reactivity:Human,Mouse,Rat

Applications:WB,ELISA

Modification:Unmodified/Total

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

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CP27B Antibody

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

CP27B Antibody

Description

cytochrome P450 family 27 subfamily B member 1(CYP27B1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008]

Catalog No

C43240

Reactivity

Human, Mouse, Rat

Applications

WB, ELISA

Modification

Unmodified/Total

Source

Polyclonal Rabbit

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

Molecular Weight (Da)

Gene Name

CYP27B1 CYP1ALPHA CYP27B

Protein Name

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (EC 1.14.13.13) (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D(3) 1-alpha-hydroxylase) (VD3 1A hydroxylase) (Calcidiol 1-monooxygenase) (Cytochrome P450 subfamily XXVIIB polypeptide 1) (Cytochrome P450C1 alpha) (Cytochrome P450VD1-alpha) (Cytochrome p450 27B1)

Human Gene ID

1594

Human Swiss Prot No.

O15528

Immunogen

Synthesized peptide derived from part region of human protein

Specificity

CP27B Polyclonal Antibody detects endogenous levels of protein.

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.