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Primary Antibodies
IGF1R (Phospho Tyr1135/1136) /Insulin Receptor β (Phospho Tyr1150/1151) (AB2305) Rabbit mAb
IGF1R (Phospho Tyr1135/1136) /Insulin Receptor β (Phospho Tyr1150/1151) (AB2305) Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M3606
Species Reactivity:Human,Mouse,Rat
Application:WB;IF;IP;ELISA
Host:Rabbit
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
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Recombinant Antibody
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IGF1R (Phospho Tyr1135/1136) /Insulin Receptor β (Phospho Tyr1150/1151) (AB2305) Rabbit mAb

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Product Details
Product Name
IGF1R (Phospho Tyr1135/1136) /Insulin Receptor β (Phospho Tyr1150/1151) (AB2305) Rabbit mAb
Description
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Catalog No
M3606
Species Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Host
Rabbit
Modifcation
phospho Y1135/1136
Clone
AB2305
Isotype
IgG
Application
WB;IF;IP;ELISA
Application Dilutions
WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5μg-4μg antibody for 200μg-400μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant protein (or fragment). This information is considered to be commercially sensitive.
Specificity
The antibody detects endogenous levels of IGF1R protein when phosphorylated at Tyr1135/1136 and Insulin Receptor β protein when phosphorylated at Tyr1150/1151. The antibody does not cross-react with IGF1R and Insulin Receptor β phosphorylated at other sites.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein A affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
IGF1R
Gene ID
3480; 3643
Human swiss
P06213; P08069
Protein Name
Insulin-like growth factor 1 receptor
Synonyms
IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221;INSR;Insulin receptor;IR;CD antigen CD220
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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