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Phospho-MKK3-S189+MKK6-S207 Rabbit mAb
Phospho-MKK3-S189+MKK6-S207 Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2750
Reactivity:Human,Mouse
Applications:WB,IF/ICC,ELISA
Modifcation:Phospho S189 + S207
Source:Rabbit
Storage and Stability:Store at -20℃/ 1 year. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20ul Size Available
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Phospho-MKK3-S189+MKK6-S207 Rabbit mAb

Confocal imaging of Raji cells (treated with pervanadate) and Raji cells (untreated) using Phospho-PLC gamma 2 (PLCG2)-Y759 Rabbit mAb (AP1519, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (AS007, dilution 1:500) (Red). DAPI was used for nuclear staining (Blue). Objective: 100x.

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Product Details
Product Name
Phospho-MKK3-S189+MKK6-S207 Rabbit mAb
Description
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]
Catalog No
M2750
Reactivity
Human, Mouse
Applications
WB, IF/ICC, ELISA
Application Dilutions
WB,1:500 - 1:1000 | IF/ICC,1:50 - 1:200 | ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modifcation
Phospho S189 + S207
Source
Rabbit
Isotype
IgG
Immunogen
A synthetic phosphorylated peptide around S189/S207 of human MKK3/MKK6.
Calculated MW (kDa)
36kDa/39kDa/31kDa/37kDa
Observed MW (kDa)Gene Name
38kDa/40kDaMP2K3/MAP2K3
Other Name
MAP2K3/MAP2K6; Phospho-MKK3-S189+MKK6-S207
Gene ID
5606/5608
Human Swiss Prot
P46734/P52564
Formulation
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃/ 1 year. Avoid freeze / thaw cycles.
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Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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