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Primary Antibodies
Phospho-Bad-S112 Rabbit mAb
Phospho-Bad-S112 Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2744
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-P,ELISA
Modifcation:Phospho S112
Source:Rabbit
Storage and Stability:Store at -20℃/ 1 year. Avoid freeze / thaw cycles.

$150
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Recombinant Antibody
20ul Size Available
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Phospho-Bad-S112 Rabbit mAb

Confocal imaging of A-431 cells (treated with EGF) and A-431 cells (untreated) using Phospho-EGFR-Y845 Rabbit mAb (AP1492, dilution 1:200) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) (AS007, dilution 1:500) (Red). The cells were counterstained with α-Tubulin Mouse mAb (AC012, dilution 1:400) followed by incubation with ABflo® 488-conjugated Goat Anti-Mouse IgG (H+L) Ab (AS076, dilution 1:500) (Green). DAPI was used for nuclear staining (Blue). Objective: 100x.

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Product Details
Product Name
Phospho-Bad-S112 Rabbit mAb
Description
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Catalog No
M2744
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-P, ELISA
Application Dilutions
WB,1:2000 - 1:8000 | IHC-P,1:500 - 1:1000 | ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modifcation
Phospho S112
Source
Rabbit
Isotype
IgG
Immunogen
A phospho specific peptide corresponding to residues surrounding S112 of human Bad.
Calculated MW (kDa)
18kDa
Observed MW (kDa)Gene Name
23kDaBAD
Other Name
BBC2; BCL2L8; Phospho-Bad-S112
Gene ID
572
Human Swiss Prot
Q92934
Formulation
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃/ 1 year. Avoid freeze / thaw cycles.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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