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CD45RB Rabbit mAb
CD45RB Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2635
Reactivity:Human
Applications:WB,IHC-P,IF/ICC,FC,ELISA
Modifcation:Unmodified
Source:Rabbit
Storage and Stability:Store at -20℃/ 1 year. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
CD45RB Rabbit mAb
Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
Catalog No
M2635
Reactivity
Human
Applications
WB, IHC-P, IF/ICC, FC, ELISA
Application Dilutions
WB,1:2000 - 1:8000 | IHC-P,1:50 - 1:200 | IF/ICC,1:50 - 1:200 | FC,1:500 - 1:1000 | ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modifcation
Unmodified
Source
Rabbit
Isotype
IgG
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 26-463 of human CD45RB (XP_006711537.1).
Calculated MW (kDa)
135kDa
Observed MW (kDa)Gene Name
200-250kDaPTPRC
Other Name
LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105; CD45RB
Gene ID
5788
Human Swiss Prot
P08575-9
Formulation
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃/ 1 year. Avoid freeze / thaw cycles.
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