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Uromodulin/UMOD Rabbit mAb
Uromodulin/UMOD Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2633
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-P,IF/ICC,ELISA
Modifcation:Unmodified
Source:Rabbit
Storage and Stability:Store at -20℃/ 1 year. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
Uromodulin/UMOD Rabbit mAb
Description
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.
Catalog No
M2633
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-P, IF/ICC, ELISA
Application Dilutions
WB,1:1000 - 1:5000 | IHC-P,1:50 - 1:200 | IF/ICC,1:50 - 1:200 | ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modifcation
Unmodified
Source
Rabbit
Isotype
IgG
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 175-324 of human Tamm Horsfall Glycoprotein(NP_003352.2).
Calculated MW (kDa)
70kDa/55kDa/115kDa
Observed MW (kDa)Gene Name
55kDaUMOD
Other Name
THP; FJHN; HNFJ; THGP; HNFJ1; MCKD2; ADTKD1; ADMCKD2; Uromodulin/UMOD
Gene ID
7369
Human Swiss Prot
P07911
Formulation
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃/ 1 year. Avoid freeze / thaw cycles.
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