25% Off Select Antibodies and ELISA Kits
Sign In/Register 0

We use cookies, check our Privacy Policies.

Flt3/CD135 Rabbit mAb
Flt3/CD135 Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2629
Reactivity:Human
Applications:FC,ELISA
Modifcation:Unmodified
Source:Rabbit
Storage and Stability:Store at -20℃/ 1 year. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
Flt3/CD135 Rabbit mAb
Description
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
Catalog No
M2629
Reactivity
Human
Applications
FC, ELISA
Application Dilutions
FC,1:100 - 1:500 | ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modifcation
Unmodified
Source
Rabbit
Isotype
IgG
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 27-163 of human Flt3/CD135 (NP_004110.2).
Calculated MW (kDa)
113kDa
Observed MW (kDa)Gene Name
160kDaFLT3
Other Name
FLK2; STK1; CD135; FLK-2; Flt3/CD135
Gene ID
2322
Human Swiss Prot
P36888
Formulation
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃/ 1 year. Avoid freeze / thaw cycles.
Related Products