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Bcl-XL Rabbit mAb
Bcl-XL Rabbit mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2545
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-P,ELISA
Modifcation:Unmodified
Source:Rabbit
Storage and Stability:Store at -20℃/ 1 year. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
Bcl-XL Rabbit mAb
Description
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Catalog No
M2545
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-P, ELISA
Application Dilutions
WB,1:1000 - 1:5000 | IHC-P,1:50-1:200 | ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modifcation
Unmodified
Source
Rabbit
Isotype
IgG
Immunogen
Recombinant protein of human Bcl-XL.
Calculated MW (kDa)
26kDa
Observed MW (kDa)Gene Name
30kDaBCL2L1
Other Name
BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S; Bcl-XL
Gene ID
598
Human Swiss Prot
Q07817
Formulation
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃/ 1 year. Avoid freeze / thaw cycles.
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