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Primary Antibodies
Cleaved IL-18 (Tyr37)
Cleaved IL-18 (Tyr37)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2330
Reactivity:Human
Applications:WB
Modifcation:Unmodified
Source:Rabbit
Storage and Stability:Store at -20℃/ 1 year. Avoid freeze / thaw cycles.

$150
# SDS #
Recombinant Antibody
20ul Size Available
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Cleaved IL-18 (Tyr37)

Western blot analysis of lysates from HeLa cells using Phospho-NF-kB p65/RelA-S529 Rabbit mAb (M2331) at 1:1000 dilution. HeLa cells were treated by TNF-α (100 ng/ml) and Calyculin A (50 nM) at 37℃ for 30 minutes.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (SA0002) at 1:10000 dilution.|Lysates/proteins: 45 μg per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 45s.

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Product Details
Product Name
Cleaved IL-18 (Tyr37)
Description
The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Catalog No
M2330
Reactivity
Human
Applications
WB
Application Dilutions
WB,1:1000 - 1:2000
Modifcation
Unmodified
Source
Rabbit
Isotype
IgG
Immunogen
A synthetic peptide corresponding to residues surrounding Tyr37 of human IL18 (NP_001553.1).
Calculated MW (kDa)
22KDa
Observed MW (kDa)Gene Name
18KDaIL-18
Other Name
mature IL-18; Cleaved IL-18 (Tyr37)
Gene ID
3606
Human Swiss Prot
Q14116
Formulation
PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃/ 1 year. Avoid freeze / thaw cycles.
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Primary Antibodies

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    • Research Areas

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