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Phospho-ZAP70-Y493
Phospho-ZAP70-Y493

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: M2267
Reactivity:Human
Applications:IF/ICC,ELISA
Modifcation:Phospho Y493
Source:Rabbit
Storage and Stability:Store at -20℃/ 1 year. Avoid freeze / thaw cycles.

$150
Product Details
Product Name
Phospho-ZAP70-Y493
Description
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Catalog No
M2267
Reactivity
Human
Applications
IF/ICC, ELISA
Application Dilutions
IF/ICC,1:50 - 1:200 | ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modifcation
Phospho Y493
Source
Rabbit
Isotype
IgG
Immunogen
A synthetic phosphorylated peptide around Y493 of human ZAP70.
Calculated MW (kDa)
70kDa
Observed MW (kDa)Gene Name
Refer to figuresZAP70
Other Name
ZAP70; ADMIO2; IMD48; SRK; STCD; STD; TZK; ZAP-70; tyrosine-protein kinase ZAP-70; Phospho-ZAP70-Y493
Gene ID
7535
Human Swiss Prot
P43403
Formulation
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Storage and Stability
Store at -20℃/ 1 year. Avoid freeze / thaw cycles.
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