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Primary Antibodies
CD117 (C-kit) (ABT233) PathoELITE™ Mouse mAb
CD117 (C-kit) (ABT233) PathoELITE™ Mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: YM6986R
Reactivity:Human
Applications:IHC
Modification:Not Modified
Source:Mouse
Storage and Stability:Store at -20°C/1 year

$70
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IHC Specialized Products
Pathology Grade Abs
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CD117 (C-kit) (ABT233) PathoELITE™ Mouse mAb

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Product Details
Product Name
CD117 (C-kit) (ABT233) PathoELITE™ Mouse mAb
Description
CD117 is a cell membrane protein encoded by the c-kit proto-oncogene and is a type III transmembrane protein tyrosine kinase growth factor receptor. CD117 is expressed in mast cells, melanocytes and interstitial cells of Cajal. CD117 is positive in 80-100% of gastric stromal sarcoma (GIST). CD117, as a specific marker for immunohistochemical examination of gastric stromal sarcoma (GIST), can be used to clinically guide the personalized target drug (Gleevec) treatment of GIST patients. CD117 can also be used to identify mast cell tumors in lymphoma and as a marker for some testicular germ cell tumors.
Catalog No
YM6986R
Reactivity
Human
Source
Mouse
Modification
Not Modified
Applications
IHC
Dilution
Ready to Use for Immunohistochemistry
Storage and Stability
Store at -20°C/1 year
Human Swiss Prot No.
P10721
Gene Name
KIT
Protein Name
CD117
Gene ID
3815
Other Name
C Kit,c-Kit,c-Kit Ligand,CD117,Kit,Kit Ligand,KIT oncogene,KIT proto oncogene receptor tyrosine kinase,KIT_HUMAN,Mast cell growth factor receptor,Mast/stem cell growth factor receptor Kit,MGF,p145 c-kit,PBT,Piebald trait protein,Proto oncogene c Kit,Proto oncogene tyrosine protein kinase Kit,Proto-oncogene c-Kit,SCF Receptor,SCFR,soluble KIT variant 1,Steel Factor Receptor,Stem cell factor receptor,tyrosine protein kinase Kit,Tyrosine-protein kinase Kit,v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog,v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Specificity
The antibody can specifically recognize human CD117 protein.
Formulation
The antibody is provided in liquid form in phosphate-buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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