tyrosine hydroxylase(TH)Homo sapiens. The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008],
Catalog No
N1457
Reactivity
Human, Mouse,Rat
Applications
IHC-p,WB
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
IHC-p1:50-200 ,WB 1:1000-2000
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.