Met (Phospho Ser985) Rabbit pAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C51146

Reactivity:Human,Mouse,Rat

Applications:IHC,WB

Modification:Phospho Specific

Source:Rabbit,polyclonal

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $300

Quantity:

Datasheet

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Met (Phospho Ser985) Rabbit pAb

Western Blot analysis of 1 A549 cell, 2 LPS 100ng/mL 30min treated ,using primary antibody at 1:1000 dilution. Secondary antibody(catalog

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Met (Phospho Ser985) Rabbit pAb

Description

MET proto-oncogene, receptor tyrosine kinase(MET) Homo sapiens This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016],

Catalog No

C51146

Reactivity

Human, Mouse, Rat

Source

Rabbit,polyclonal

Modification

Phospho Specific

Applications

IHC, WB

Dilution

WB 1:500-2000 IHC 1:50-200

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)

Molecular Weight (Da or kDa)

Gene Name

MET

Protein Name

Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)

Human Gene ID

4233

Human Swiss Prot No.

P08581

Immunogen

Synthesized peptide derived from human Met (Phospho Ser985)

Specificity

This antibody detects endogenous levels of Met (Phospho Ser985) Rabbit pAb at Human, Mouse,Rat

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.