MKP-1 (Phospho Ser323) Rabbit pAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C51138

Reactivity:Human,Mouse,Rat

Applications:IHC,WB

Modification:Phospho Specific

Source:Rabbit,polyclonal

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $300

Quantity:

Datasheet

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MKP-1 (Phospho Ser323) Rabbit pAb

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

MKP-1 (Phospho Ser323) Rabbit pAb

Description

dual specificity phosphatase 1(DUSP1) Homo sapiens The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferati

Catalog No

C51138

Reactivity

Human, Mouse, Rat

Source

Rabbit,polyclonal

Modification

Phospho Specific

Applications

IHC, WB

Dilution

WB 1:500-2000 IHC 1:50-200

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

Dual specificity protein phosphatase 1 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH1) (Mitogen-activated protein kinase phosphatase 1) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100)

Molecular Weight (Da or kDa)

Gene Name

DUSP1 CL100 MKP1 PTPN10 VH1

Protein Name

Human Gene ID

1843

Human Swiss Prot No.

P28562

Immunogen

Synthesized peptide derived from human MKP-1 (Phospho Ser323)

Specificity

This antibody detects endogenous levels of MKP-1 (Phospho Ser323) Rabbit pAb at Human, Mouse,Rat