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Cyclin E1 (Phospho Ser399) Rabbit pAb
Cyclin E1 (Phospho Ser399) Rabbit pAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C51106
Reactivity:Human,Mouse,Rat
Applications:IHC,WB
Modification:Phospho Specific
Source:Rabbit,polyclonal
Storage and Stability:Store at -20°C/1 year

$300
Product Details
Product Name
Cyclin E1 (Phospho Ser399) Rabbit pAb
Description
cyclin E1(CCNE1) Homo sapiens The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in
Catalog No
C51106
Reactivity
Human, Mouse, Rat
Source
Rabbit,polyclonal
Modification
Phospho Specific
Applications
IHC, WB
Dilution
WB 1:500-2000 IHC 1:50-200
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
G1/S-specific cyclin-E1
Molecular Weight (Da or kDa)
Gene Name
CCNE1 CCNE
Protein Name
G1/S-specific cyclin-E1
Human Gene ID
898
Human Swiss Prot No.
P24864
Immunogen
Synthesized peptide derived from human Cyclin E1 (Phospho Ser399)
Specificity
This antibody detects endogenous levels of Cyclin E1 (Phospho Ser399) Rabbit pAb at Human, Mouse,Rat
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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