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Primary Antibodies
BRCA1 (Phospho Ser1497) Rabbit pAb
BRCA1 (Phospho Ser1497) Rabbit pAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C51104
Reactivity:Human,Mouse,Rat
Applications:IHC,WB
Modification:Phospho Specific
Source:Rabbit,polyclonal
Storage and Stability:Store at -20°C/1 year

$300
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BRCA1 (Phospho Ser1497) Rabbit pAb

Western Blot analysis of mouse brain rat brain ,using primary antibody at 1:1000 dilution. Secondary antibody(catalog

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Product Details
Product Name
BRCA1 (Phospho Ser1497) Rabbit pAb
Description
BRCA1, DNA repair associated(BRCA1) Homo sapiens This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript varian
Catalog No
C51104
Reactivity
Human, Mouse, Rat
Source
Rabbit,polyclonal
Modification
Phospho Specific
Applications
IHC, WB
Dilution
WB 1:500-2000 IHC 1:50-200
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Breast cancer type 1 susceptibility protein (EC 6.3.2.-) (RING finger protein 53)
Molecular Weight (Da or kDa)
205kD
Gene Name
BRCA1 RNF53
Protein Name
Breast cancer type 1 susceptibility protein (EC 6.3.2.-) (RING finger protein 53)
Human Gene ID
672
Human Swiss Prot No.
P38398
Immunogen
Synthesized peptide derived from human BRCA1 (Phospho Ser1497)
Specificity
This antibody detects endogenous levels of BRCA1 (Phospho Ser1497) Rabbit pAb at Human, Mouse,Rat
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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