HER4 (Phospho Tyr1242) Rabbit pAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C51089

Reactivity:Human,Mouse,Rat

Applications:IHC,WB

Modification:Phospho Specific

Source:Rabbit,polyclonal

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $300

Quantity:

Datasheet

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HER4 (Phospho Tyr1242) Rabbit pAb

Western Blot analysis of mouse brain tissue, MCF-7 rat brain tissue using primary antibody at 1:1000 dilution 4°C, overnight. Secondary antibody(catalog

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

HER4 (Phospho Tyr1242) Rabbit pAb

Description

erb-b2 receptor tyrosine kinase 4(ERBB4) Homo sapiens This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],

Catalog No

C51089

Reactivity

Human, Mouse, Rat

Source

Rabbit,polyclonal

Modification

Phospho Specific

Applications

IHC, WB

Dilution

WB 1:500-2000 IHC 1:50-200

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]

Molecular Weight (Da or kDa)

Gene Name

ERBB4 HER4

Protein Name

Human Gene ID

2066

Human Swiss Prot No.

Q15303

Immunogen

Synthesized peptide derived from human HER4 (Phospho Tyr1242)

Specificity

This antibody detects endogenous levels of HER4 (Phospho Tyr1242) Rabbit pAb at Human, Mouse,Rat