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C-RAF (Phospho Tyr340) Rabbit pAb
C-RAF (Phospho Tyr340) Rabbit pAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C51088
Reactivity:Human,Mouse,Rat
Applications:IHC,WB
Modification:Phospho Specific
Source:Rabbit,polyclonal
Storage and Stability:Store at -20°C/1 year

$300
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C-RAF (Phospho Tyr340) Rabbit pAb

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Product Details
Product Name
C-RAF (Phospho Tyr340) Rabbit pAb
Description
Raf-1 proto-oncogene, serine/threonine kinase(RAF1) Homo sapiens This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008],
Catalog No
C51088
Reactivity
Human, Mouse, Rat
Source
Rabbit,polyclonal
Modification
Phospho Specific
Applications
IHC, WB
Dilution
WB 1:500-2000 IHC 1:50-200
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Molecular Weight (Da or kDa)
71kD
Gene Name
RAF1 RAF
Protein Name
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Human Gene ID
5894
Human Swiss Prot No.
P04049
Immunogen
Synthesized peptide derived from human C-RAF (Phospho Tyr340)
Specificity
This antibody detects endogenous levels of C-RAF (Phospho Tyr340) Rabbit pAb at Human, Mouse,Rat
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
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Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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