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Primary Antibodies
Anti-Human Proliferating Cell Nuclear Antigen (ABT221) Mouse Monoclonal Antibody
Anti-Human Proliferating Cell Nuclear Antigen (ABT221) Mouse Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0442
Reactivity:Human
Application:IHC,WB
Modification:Unmodified/ Total
Source:Monoclonal Mouse
Storage and Stability:Stable at -20°C for at least 1 year.

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Immunohistochemical
Sample Sized mAbs 5477
Pathology Grade Abs
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Anti-Human Proliferating Cell Nuclear Antigen (ABT221) Mouse Monoclonal Antibody

Human colon tissue was stained with Anti-Proliferating Cell Nuclear Antigen (ABT221) Antibody

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Product Details
Product Name
Anti-Human Proliferating Cell Nuclear Antigen (ABT221) Mouse Monoclonal Antibody
Description
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],
Catalog No
V0442
Reactivity
Human
Application
IHC,WB
Modification
Unmodified/ Total
Source
Monoclonal Mouse
Storage and Stability
Stable at -20°C for at least 1 year.
Other Name
ATLD2, cb16, Cyclin, DNA polymerase delta auxiliary protein, etID36690.10, fa28e03, fb36g03, HGCN8729, MGC8367, Mutagen-sensitive 209 protein, OTTHUMP00000030189, OTTHUMP00000030190, PCNA, Pcna/cyclin, PCNA_HUMAN, PCNAR, Polymerase delta accessory protein, Proliferating cell nuclear antigen, wu:fa28e03, wu:fb36g03
Gene Name
PCNA
UniProtKB
P12004
Clone ID
ABT221
Isotype
IgG2b, kappa
Localization
Nuclear
Positive Tissue Control
Tonsil/ Colon
Specificity
The antibody can specifically recognize human PCNA protein. In western blotting of Hela, A431 and HEK293 cell lysates, the antibody can label a 30 kDa band corresponding to PCNA.
Formulation
PBS, pH7.2, 0.03% Proclin 300, 50% glycerol
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Publications (2)
CD147 mediates epidermal malignant transformation through the RSK2/AP-1 pathway JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH Xiang Chen IHC Mouse

Author: Available in link provided

Date of Publication : Available in link provided

TRAF6 regulates autophagy and apoptosis of melanoma cells through c-Jun/ATG16L2 signaling pathway. Cong Peng IHC Mouse 1:350 SK-Mel-5 cell-xenograft

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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