BCL2, apoptosis regulator(BCL2)Homo sapiens. This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
Catalog No
N0057
Reactivity
Human,Mouse
Applications
IHC-p,IF/ICC,FCM,ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
Purification
Affinity purification
Concentration
Storage and Stability
-20°C/1 year
Other Name
BCL2; Apoptosis regulator Bcl-2
Molecular Weight (Da)
Gene Name
BCL2
Protein Name
Apoptosis regulator Bcl-2
Human Gene ID
596
Human Swiss Prot No.
P10415
Immunogen
Synthetic peptide corresponding to residues surrounding Bcl-2, conjugated to KLH.
Specificity
Bcl-2 Monoclonal Antibody detects endogenous levels of Bcl-2 protein.
Immunofluorescence analysis of NIH/3T3 cells using Bcl-2 Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Immunohistochemistry analysis of paraffin-embedded colon cancer tissues (left) and human brain tissues (right) with DAB staining using Bcl-2 Monoclonal Antibody.
