CD4 molecule(CD4)Homo sapiens. This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010],
Catalog No
N0124
Reactivity
Human
Applications
ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
ELISA: 1/10000. Not yet tested in other applications.
