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Crk II Monoclonal Antibody
Crk II Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0165
Reactivity:Human
Applications:WB,IHC-p,IF/ICCFCM,ELISA
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$210
Product Details
Product Name
Crk II Monoclonal Antibody
Description
CRK proto-oncogene, adaptor protein(CRK)Homo sapiens. This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008],
Catalog No
N0165
Reactivity
Human
Applications
WB,IHC-p,IF/ICC,FCM,ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
Purification
Affinity purification
Concentration
Storage and Stability
-20°C/1 year
Other Name
CRK; Adapter molecule crk; Proto-oncogene c-Crk; p38
Molecular Weight (Da)
Gene Name
CRK
Protein Name
Adapter molecule crk
Human Gene ID
1398
Human Swiss Prot No.
P46108
Immunogen
Purified recombinant fragment of human Crk II expressed in E. Coli.
Specificity
Crk II Monoclonal Antibody detects endogenous levels of Crk II protein.
Formulation
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
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