SMN1 Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0586

Reactivity:Human,Monkey

Applications:WB,IHC-p,IF(paraffin section),FCM,ELISA

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $210

Quantity:

Datasheet

SDS

Neurobiology

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SMN1 Monoclonal Antibody

Western Blot analysis using SMN1 Monoclonal Antibody against HepG2 (1). HeLa (2). K562 (3). Jurkat (4). SKBR-3 (5). A431 (6) and Cos7 (7) cell lysate.

Delivery

Freight Charges

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

SMN1 Monoclonal Antibody

Description

survival of motor neuron 1, telomeric(SMN1) Homo sapiens. This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein. However, mutations in this gene, the telomeric copy, are associated with spinal muscular atrophy; mutations in the centromeric copy do not lead to disease. The centromeric copy may be a modifier of disease caused by mutation in the telomeric copy. The critical sequence difference between the two genes is a single nucleotide in exon 7, which is thought to be an exon splice enhancer. Note that the nine exons of both the telomeric and centromeric copies are des

Catalog No

N0586

Reactivity

Human,Monkey

Applications

WB,IHC-p,IF(paraffin section),FCM,ELISA

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.

Purification

Affinity purification

Concentration

Storage and Stability

-20°C/1 year

Other Name

SMN1; SMN; SMNT; SMN2; SMNC; Survival motor neuron protein; Component of gems 1; Gemin-1

Molecular Weight (Da)

Gene Name

SMN1

Protein Name

Survival motor neuron protein