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PEG10 mouse mAb
PEG10 mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0919
Reactivity:Human
Applications:WB,IP
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
Product Details
Product Name
PEG10 mouse mAb
Description
This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag-like protein (with a CCHC-type zinc finger domain) from RF1; and a longer, gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS). While -1 FS has been observed in RNA viruses and transposons in both prokaryotes and eukaryotes, this gene represents the first example of -1 FS in a eukaryotic cellular gene. This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS. It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation, differentiation and apoptosis.
Catalog No
N0919
Reactivity
Human
Applications
WB,IP
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
wb 1:1000
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
AA407948;Edr;Embryonal carcinoma differentiation regulated;Embryonal carcinoma differentiation-regulated protein;HB 1;HB1;KIAA1051;Mammalian retrotransposon-derived protein 2;Mar2;Mart2;MEF3 like 1;MEF3-like protein 1;MEF3L;MEF3L1;MyEF 3;Myelin expression factor 3-like protein 1;Paternally expressed 10;Paternally expressed gene 10 ORF1;Paternally expressed gene 10 protein;Peg10;PEG10 protein;PEG10_HUMAN;Putative uncharacterized protein PEG10;Retrotransposon gag domain containing 3;Retrotransposon gag domain-containing protein 3;Retrotransposon-derived gag-like polyprotein; Retrotransposon-derived protein PEG10;RGAG3;Ty3/Gypsy-like protein.
Molecular Weight (Da)
Gene Name
peg10
Protein Name
Human Gene ID
23089
Human Swiss Prot No.
Q86TG7
Immunogen
Purified recombinant human PEG10 protein fragments expressed in E.coli.
Specificity
This antibody detects endogenous levels of PEG10 and does not cross-react with related proteins.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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