HER2/ErbB2 mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1016

Reactivity:Transfected

Applications:WB

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $160

Quantity:

Datasheet

SDS

Membrane Receptors

HER2/ErbB2 mouse mAb

Western blot detection of HER2/ErbB2 fragment in CHO-K1 cell lysate (B) and CHO-K1 transfected by pEGFP-C1-HER2/ErbB2 (A) cell lysate using HER2/ErbB2 mouse mAb (1:1000 diluted).Predicted band size: 55kDa.Observed band size:55kDa.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

HER2/ErbB2 mouse mAb

Description

erb-b2 receptor tyrosine kinase 2(ERBB2)Homo sapiens. This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding d

Catalog No

N1016

Reactivity

Transfected

Applications

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

wb dilution 1:1000

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;C erb B2/neu protein;CD340;CD340 antigen;Cerb B2/neu protein;CerbB2;Erb b2 receptor tyrosine kinase 2;ERBB2;ERBB2_HUMAN;HER 2;HER 2/NEU;HER2;Herstatin;Human epidermal growth factor receptor 2;Metastatic lymph node gene 19 protein;MLN 19;MLN19;NEU;NEU proto oncogene;Neuro/glioblastoma derived oncogene homolog;Neuroblastoma/glioblastoma derived oncogene homolog;NGL;p185erbB2;Proto-oncogene c-ErbB-2;Proto-oncogene Neu;Receptor tyrosine-protein kinase erbB-2;TKR1;Tyrosine kinase type cell surface receptor HER2;Tyrosine kinase-type cell surface receptor HER2;V erb b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog);V erb b2 avian erythroblastic leukemia viral oncogene homolog 2;V erb b2 avian erythroblastic leukemia viral oncoprotein 2;V erb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian);V erb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog;Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian).

Molecular Weight (Da)

Gene Name

erbb2

Protein Name

Human Gene ID

2064

Human Swiss Prot No.

P04626

Immunogen

Purified recombinant human HER2/ErbB2 protein fragments expressed in E.coli.

Specificity

Transfected Only.