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p53 Monoclonal Antibody(6C4)
p53 Monoclonal Antibody(6C4)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1317
Reactivity:Human
Applications:WB,IHC-p,IF/ICC
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
Product Details
Product Name
p53 Monoclonal Antibody(6C4)
Description
tumor protein p53(TP53)Homo sapiens. This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],
Catalog No
N1317
Reactivity
Human
Applications
WB,IHC-p,IF/ICC
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB: 1:2000 IHC: 1:200 IF: 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
Molecular Weight (Da)
43653
Gene Name
TP53
Protein Name
Cellular tumor antigen p53
Human Gene ID
7157
Human Swiss Prot No.
P04637
Immunogen
Synthetic Peptide of p53
Specificity
The antibody detects endogenous p53 proteins.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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