HER2 Monoclonal Antibody(3C9)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1344

Reactivity:Human

Applications:WB

Modification:Unmodfied/ Total

Source:Monoclonal Mouse

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $160

Quantity:

Datasheet

SDS

Membrane Receptors

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HER2 Monoclonal Antibody(3C9)

Western blot analysis of 1) Hela. 2) 293. 3) Jurkat. diluted at 1:2000.

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

HER2 Monoclonal Antibody(3C9)

Description

erb-b2 receptor tyrosine kinase 2(ERBB2)Homo sapiens. This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding d

Catalog No

N1344

Reactivity

Human

Applications

Modification

Unmodfied/ Total

Source

Monoclonal Mouse

Dilution

WB: 1:1000

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

Storage and Stability

-20°C/1 year

Other Name

ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340

Molecular Weight (Da)

137910

Gene Name

ERBB2

Protein Name

Receptor tyrosine-protein kinase erbB-2

Human Gene ID

2064

Human Swiss Prot No.

P04626

Immunogen

Synthetic Peptide of HER2