keratin 18(KRT18)Homo sapiens. KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Catalog No
N1360
Reactivity
Human,Mouse,Rat
Applications
WB,IF/ICC
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB: 1:1000 -3000 IF: 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
KRT18; CYK18; PIG46; Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
Molecular Weight (Da)
47927
Gene Name
KRT18
Protein Name
Keratin type I cytoskeletal 18
Human Gene ID
3875
Human Swiss Prot No.
P05783
Immunogen
Recombinant Protein of Keratin type I cytoskeletal 18
Specificity
The antibody detects endogenous Cytokeratin 18 protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.