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Primary Antibodies
PARP Monoclonal Antibody(M3)
PARP Monoclonal Antibody(M3)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1396
Reactivity:Human,Chicken(testedbyourcustomer）
Applications:WB
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
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Tumor Suppressors/Apoptosis
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PARP Monoclonal Antibody(M3)

Western blot analysis of 1) Hela. 2) 293T. 3) Jurkat. diluted at 1:2000. cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003.Inventbiotech.MN.USA).

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Product Details
Product Name
PARP Monoclonal Antibody(M3)
Description
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],
Catalog No
N1396
Reactivity
Human,Chicken(testedbyourcustomer）
Applications
WB
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
WB: 1:1000-3000
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)
Molecular Weight (Da)
Gene Name
PARP1
Protein Name
Poly [ADP-ribose] polymerase 1
Human Gene ID
142
Human Swiss Prot No.
P09874
Immunogen
Synthetic Peptide of PARP
Specificity
The antibody detects endogenous PARP protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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Publications (6)
Modulations of Keap1-Nrf2 signaling axis by TIIA ameliorated the oxidative stress-induced myocardial apoptosis. FREE RADICAL BIOLOGY AND MEDICINE Free Radical Bio Med. 2018 Feb;115:191 WB Mouse Neonatal rat ventricular myocytes (NRVMs)

Author: Available in link provided

Date of Publication : Available in link provided

The induction of apoptosis and autophagy in human hepatoma SMMC-7721 cells by combined treatment with vitamin C and polysaccharides extracted from Grifola frondosa. APOPTOSIS 2017 Sep 11 WB Human SMMC-7721 cell

Author: Available in link provided

Date of Publication : Available in link provided

Coptisine Induces Apoptosis in Human Hepatoma Cells Through Activating 67-kDa Laminin Receptor/cGMP Signaling. Frontiers in Pharmacology 2018 May 18 WB Human 1:500 SMMC7721 cell, HepG2 Cell

Author: Available in link provided

Date of Publication : Available in link provided

High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma. TUMOR BIOLOGY Tumor Biol. 2015 Apr;36(4):2569-2581 WB Human HepG2 cell, Huh7 HCC cell

Author: Available in link provided

Date of Publication : Available in link provided

High expression of PINK1 promotes proliferation and chemoresistance of NSCLC. ONCOLOGY REPORTS Oncol Rep. 2017 Apr;37(4):2137-2146 WB Human NSCLC tissues A549 cell, H1299 cell

Author: Available in link provided

Date of Publication : Available in link provided

Effect of metformin on apoptosis, cell cycle arrest migration and invasion of A498 cells. Molecular Medicine Reports 2014 Mar 31 WB Human A498 cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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