progesterone receptor(PGR) Homo sapiens. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015],
Catalog No
N1506
Reactivity
Human,Mouse,Rat
Applications
IHC-p,IF/ICC
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
IHC: 1:200 IF: 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Concentration
Storage and Stability
-20°C/1 year
Other Name
PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3
Molecular Weight (Da)
Gene Name
PGR
Protein Name
Progesterone receptor
Human Gene ID
5241
Human Swiss Prot No.
P06401
Immunogen
Synthetic Peptide of PR
Specificity
The antibody detects endogenous PR protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Immunohistochemical analysis of paraffin-embedded Mouse-testis tissue. 1.PR Monoclonal Antibody(Z15) was diluted at 1:200(4°C.overnight). 2. Sodium citrate pH 6.0 was used for antibody retrieval(>98°C.20min). 3.Secondary antibody was diluted at 1:200(room temperature. 30min). Negative control was used by secondary antibody only.
Immunohistochemical analysis of paraffin-embedded Rat-testis tissue. 1.PR Monoclonal Antibody(Z15) was diluted at 1:200(4°C.overnight). 2. Sodium citrate pH 6.0 was used for antibody retrieval(>98°C.20min). 3.Secondary antibody was diluted at 1:200(room temperature. 30min). Negative control was used by secondary antibody only.
Immunohistochemical analysis of paraffin-embedded Human-uterus tissue. 1.PR Monoclonal Antibody(Z15) was diluted at 1:200(4°C.overnight). 2. Sodium citrate pH 6.0 was used for antibody retrieval(>98°C.20min). 3.Secondary antibody was diluted at 1:200(room temperature. 30min). Negative control was used by secondary antibody only.
