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Primary Antibodies
AKT mouse Monoclonal Antibody(1E11)
AKT mouse Monoclonal Antibody(1E11)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1647
Reactivity:Human,Rat,Mouse
Applications:IHC-p,IF(paraffin section)
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$160
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AKT mouse Monoclonal Antibody(1E11)

Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Akt Mouse mAb diluted at 1:200.

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Product Details
Product Name
AKT mouse Monoclonal Antibody(1E11)
Description
AKT serine/threonine kinase 1(AKT1) Homo sapiens. The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
Catalog No
N1647
Reactivity
Human,Rat,Mouse
Applications
IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
IHC 1:100-200
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
AKT1
Molecular Weight (Da)
Gene Name
AKT1/AKT2/AKT3
Protein Name
AKT1
Human Gene ID
207
Human Swiss Prot No.
P31749
Immunogen
Synthetic Peptide of AKT at AA range of 60-140
Specificity
AKT protein detects endogenous levels of AKT1
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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