Janus kinase 2(JAK2) Homo sapiens. This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],
Catalog No
N1688
Reactivity
Human,Mouse,Rat
Applications
IHC-p,IF(paraffin section)
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
IHC-p 1:50-300
Purification
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
