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P53 mouse mAb(PT0337)
P53 mouse mAb(PT0337)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1731
Reactivity:Human
Applications:IHC-p,IF(paraffin section),WB
Modification:Unmodfied/ Total
Source:Monoclonal Mouse/IgG1,Kappa
Storage and Stability:-20°C/1 year

$160
Product Details
Product Name
P53 mouse mAb(PT0337)
Description
tumor protein p53(TP53)Homo sapiens. This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],
Catalog No
N1731
Reactivity
Human
Applications
IHC-p,IF(paraffin section),WB
Modification
Unmodfied/ Total
Source
Monoclonal Mouse/IgG1, Kappa
Dilution
IHC-p 1:100-300,WB 1:500-2000
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Molecular Weight (Da)
Gene Name
TP53 P53
Protein Name
P53
Human Gene ID
7157
Human Swiss Prot No.
P04637
Immunogen
Synthesized peptide derived from human P53
Specificity
This antibody detects endogenous levels of human P53
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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