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PD-1 (PT1707) mouse mAb

Catalog No : N1763
  • Reactivity
    Human,Mouse
  • Applications
    IHC-p,IF(paraffin section)
  • Modification
    Unmodfied/ Total
  • Source
    Monoclonal Mouse/IgG1,Kappa
  • Storage and Stability
    -20°C/1 year
  • Size
    50 ul
  • Price/Quantity
    $190
  • Quantity
Details
  • Product Name
    PD-1 (PT1707) mouse mAb
  • Description
    programmed cell death 1(PDCD1) Homo sapiens. This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008],
  • Catalog No
    N1763
  • Reactivity
    Human, Mouse
  • Applications
    IHC-p,IF(paraffin section)
  • Modification
    Unmodfied/ Total
  • Source
    Monoclonal Mouse/IgG1, Kappa
  • Dilution
    WB 500-2000 IHC-p 1:100-500
  • Purification
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Concentration
  • Storage and Stability
    -20°C/1 year
  • Other Name
  • Molecular Weight (Da)
  • Gene Name
    PDCD1 PD1
  • Protein Name
    Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279)
  • Human Gene ID
    5133
  • Human Swiss Prot No.
    Q15116
  • Immunogen
    Synthesized peptide derived from human PD-1
  • Specificity
    This antibody detects endogenous levels of human PD-1. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.