Epithelial Membrane Antigen(MUC1) (PT0132) mouse mAb

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Catalog No: N1783

Reactivity:Human,Mouse

Applications:IHC-p,IF(paraffin section)

Modification:Unmodfied/ Total

Source:Monoclonal Mouse/IgG2b,Kappa

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $190

Quantity:

Datasheet

SDS

Immunohistochemical

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Epithelial Membrane Antigen(MUC1) (PT0132) mouse mAb

Immunohistochemical analysis of paraffin-embedded Esophageal squamous carcinoma. 1. Antibody was diluted at 1:200(4° overnight). 2. TRIS-EDTA of pH8.0 was used for antigen retrieval. 3.Secondary antibody was diluted at 1:200(room temperature. 30min).

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Epithelial Membrane Antigen(MUC1) (PT0132) mouse mAb

Description

mucin 1, cell surface associated(MUC1) Homo sapiens. This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate sp

Catalog No

N1783

Reactivity

Human, Mouse

Applications

IHC-p,IF(paraffin section)

Modification

Unmodfied/ Total

Source

Monoclonal Mouse/IgG2b, Kappa

Dilution

IHC-p 1:100-500，WB 1:500-2000

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

Storage and Stability

-20°C/1 year

Other Name

Molecular Weight (Da)

Gene Name

MUC1 PUM

Protein Name

Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)], CA 15-3, CA15 3, CA 15.3 , CA15-3, CA15.3

Human Gene ID

4582

Human Swiss Prot No.

P15941

Immunogen

Synthesized peptide derived from human Epithelial Membrane Antigen(MUC1)

Specificity

This antibody detects endogenous levels of human Epithelial Membrane Antigen(MUC1). Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.