cadherin pan (PT1718) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1821

Reactivity:Human,Mouse

Applications:IHC-p,IF/ICC

Modification:Unmodfied/ Total

Source:Monoclonal Mouse/IgG1,Kappa

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $190

Quantity:

Datasheet

SDS

Immunohistochemical

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cadherin pan (PT1718) mouse mAb

Immunohistochemical analysis of paraffin-embedded Colon carcinoma. 1. Antibody was diluted at 1:200(4° overnight). 2. Citrate buffer of pH6.0 was used for antigen retrieval. 3.Secondary antibody was diluted at 1:200(room temperature. 30min).

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

cadherin pan (PT1718) mouse mAb

Description

cadherin 1(CDH1)Homo sapiens. This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015],

Catalog No

N1821

Reactivity

Human, Mouse

Applications

IHC-p,IF/ICC

Modification

Unmodfied/ Total

Source

Monoclonal Mouse/IgG1, Kappa

Dilution

IHC-p 1:100-500，WB 1:500-2000，IF 1:500-200

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

Storage and Stability

-20°C/1 year

Other Name

Molecular Weight (Da)

Gene Name

cadherin pan

Protein Name

cadherin pan

Human Gene ID

Human Swiss Prot No.

P12830/P19022/P22223/P55283/O75309

Immunogen

Synthesized peptide derived from human cadherin pan

Specificity

This antibody detects endogenous levels of human cadherin pan. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.